Pediatric anesthesia & critical care
Transnasal humidified rapid-insufflation ventilatory exchange (transnasal humidified rapid insufflation ventilatory exchange (THRIVE)) use in a pediatric population: A prospective, randomized controlled trial
Authors' conclusion
THRIVE was not superior to SOC for reducing the number of patients who experienced desaturations or surgical interruptions, though it may have some benefit for reducing the total number of desaturation events in those who desaturate.
Study context
- Population
- Children aged 2 months to 18 years undergoing airway examinations or airway procedures under GA
- Participants
- 144 children
- Comparison
- THRIVE vs standard of care during airway procedures under GA
- Primary endpoint
- Participants with ≥1 relative desaturation event (4 % drop from average baseline saturation, oxygen desaturation index)
Methodological detailsprospective, multicentre (three pediatric sites), 1:1 randomisation
- Prospective
- Multicentre (three pediatric sites)
- 1:1 randomisation
Primary result
As reported in the abstract
- THRIVE vs standard of care (SOC): P = 0.18
Further findings
| Outcome | P value |
|---|---|
| Total number of relative desaturation events (accounting for multiple events per participant)Difference | P = 0.04 |
Surgical interruptions due to airway conditions
- No differences between THRIVE and SOC
Original publication
Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) use in a pediatric population: A prospective, randomized controlled trial. J Clin Anesth. Published 3 January 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →