Cardiac arrest & resuscitation
Temperature Control After In-Hospital Cardiac Arrest: Outcomes From the Discover In-Hospital Cardiac Arrest Cohort
Main finding · Survival to hospital dischargeResult — go to the resultAdjusted odds ratio 1.19 95% CI 0.79–1.80Authors' conclusion
Among comatose IHCA survivors, more than half received no documented temperature control strategy. Those with a strategy were less likely to have a fever and more likely to receive temperature control directed therapy, but showed no difference in survival, functional, or neurologic outcomes.
Study context
- Population
- Adults with in-hospital cardiac arrest (IHCA) who survived initial resuscitation and remained comatose and eligible for temperature control; 24 hospital systems, 46 hospitals, October 2023 to June 2024comatose, eligible
- Participants
- 615 adults
- Exposure
- Documented temperature control strategy vs none in the first 24 hours after arrest
- Documented temperature control strategyn = 273
- Outcome
- Survival to hospital discharge
Methodological detailsmulticentre, international
- Multicentre
- International
Main finding
As reported in the abstract
Adjusted odds ratio
1.19
95% CI 0.79–1.80
P = 0.42
By group
Strategy vs No strategy
aOR 1.19 (95% CI 0.79–1.80); P = 0.42
Observational data: associations, not effects.
Further findings
| Outcome | No documented temperature control strategy | aOR (95% CI) | P value | |
|---|---|---|---|---|
| Receipt of temperature control therapyStrategy vs No strategy | 21.3 (12.3–36.7) | P < 0.01 | ||
| Fever (temperature ≥ 38°C) · first 24 hours after resuscitationStrategy vs No strategy | 0.63 (0.43–0.92) | P = 0.02 | ||
| Favorable functional outcome (modified Rankin Scale ≤ 3)Strategy vs No strategy | 10.5% | 1.14 (0.53–2.42) | P = 0.74 | |
| Favorable neurologic outcome (Cerebral Performance Category ≤ 2)Strategy vs No strategy | 12.3% | 1.15 (0.63–2.12) | P = 0.65 | |
| 0.050.21520Adjusted odds ratio (log scale) |
- Favorable functional outcome (modified Rankin Scale ≤ 3): Strategy 9.9%
- Favorable neurologic outcome (Cerebral Performance Category ≤ 2): Strategy 12.8%
Hospital system proportions with temperature control strategy
- Ranged from 0% to 100%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Temperature Control After In-Hospital Cardiac Arrest: Outcomes From the Discover In-Hospital Cardiac Arrest Cohort. Crit Care Med. Published 20 March 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →