Hemodynamics, fluids & transfusion

Temperature effect on coagulation function in mild hypothermic patients undergoing thoracic surgeries: thromboelastography (TEG) versus standard tests

Perioper Med (Lond)Published Comparative study

Authors' conclusion

Mild hypothermia significantly impaired coagulation function in patients receiving thoracic surgeries, which could be detected by TEGs other than the standard coagulation tests.

Study context

Population
Patients undergoing thoracic surgeries
Participants
64 patients
Comparison
Active vs passive warming during thoracic surgery; TEG vs standard coagulation tests
Outcome
Coagulation function by TEG parameters and standard coagulation tests

Main finding

As reported in the abstract

TEG parameters (mild hypothermia vs normothermia)
MA decreased with mild hypothermia: 59.4 ± 4.5 mm vs 64.2 ± 5.7 mm
p = 0.04
α angle decreased with mild hypothermia: 70.4 ± 5.2° vs 74.9 ± 4.4°
p = 0.05
ACT prolonged with mild hypothermia: 122.2 ± 19.3 s vs 117.3 ± 15.2 s
p = 0.01
K time prolonged with mild hypothermia: 1.9 ± 1.0 s vs 1.3 ± 0.4 min
p = 0.02

Further findings

TEG at actual core body temperature (passive warming samples)

More impaired coagulation than TEG incubated at 37 °C

Postoperative shivering and waking time

Significantly increased in mild hypothermic patients

Original publication

Temperature effect on coagulation function in mild hypothermic patients undergoing thoracic surgeries: thromboelastography (TEG) versus standard tests. Perioper Med (Lond). Published 12 June 2024. doi:10.1186/s13741-024-00405-8

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