Obstetric anesthesia

The ability of shock index to predict refractory postpartum haemorrhage: A secondary analysis of the prospective and multicentre HELP MOM study

Eur J AnaesthesiolPublished Secondary analysis of a multicentre prospective observational study

Authors' conclusion

The shock index measured at the start of sulprostone infusion and at the worst time after enrolment, has poor discriminative power to predict this event.

Study context

Population
Patients with severe PPH (blood loss ≥1500 ml requiring sulprostone)316 analysed
Participants
332 patients
Comparison
Shock index at T0 and T1 as predictors of refractory PPH
Primary endpoint
Predictive ability of the shock index (univariate and multivariate logistic regression and AUROC)
Methodological detailsNovember 2014 to November 2016
  • November 2014 to November 2016

Primary result

As reported in the abstract

Refractory PPH

T0

0.614

95% CI 0.549 to 0.678

AUC

T1

0.681

95% CI 0.616 to 0.746

AUC

High shock index, independently associated
Odds ratio (95% CI)P value
T0
3.07(1.22–7.89)
P = 0.017
T1
5.28(2.25–12.8)
P < 0.001
Prevalence of refractory PPH
35.4% (112/316)

Original publication

The ability of shock index to predict refractory postpartum haemorrhage: A secondary analysis of the prospective and multicentre HELP MOM study. Eur J Anaesthesiol. Published 21 February 2025. doi:10.1097/eja.0000000000002142

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