Thromboelastometry-guided treatment algorithm in postpartum haemorrhage: a randomised, controlled pilot trial
Authors' conclusion
ROTEM-guided treatment of postpartum haemorrhage could have a plasma-sparing effect but possibly only a small reduction in total blood loss.
Study context
- Population
- Parturients with PPH of more than 1500 ml54 analysed
- Participants
- 60 participants
- Comparison
- Rotational thromboelastometry (ROTEM)-guided vs conventional treatment
- Primary endpoint
- Consumption of blood products
Methodological detailspilot, parallel design
- Pilot
- Parallel design
Primary result
As reported in the abstract
RBC units transfused
P = 0.399
Secondary outcomes
Total estimated blood loss
P = 0.033
| Outcome | ROTEM | Control | P value |
|---|---|---|---|
| OctaplasLG® units given | median 0 (IQR 0–0) units | median 0 (IQR 0–2) units | P = 0.030 |
Safety
Thromboembolic complications, infections, transfusion reactions
- No differences observed in secondary outcomes
Original publication
Thromboelastometry-guided treatment algorithm in postpartum haemorrhage: a randomised, controlled pilot trial. Br J Anaesth. Published 7 December 2022. doi:10.
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