Cardiac arrest & resuscitation
The association between intra-arrest arterial blood pressure and return of spontaneous circulation in out-of-hospital cardiac arrest
Main finding · ROSC prediction by maximum DBPResult — go to the resultOdds ratio 1.05 95 % CI 1.03–1.08Authors' conclusion
This study supports the use of arterial DBP as an important haemodynamic parameter for goal-directed resuscitation in adult OHCA.
Study context
- Population
- Adult (≥18 years) medical out-of-hospital cardiac arrest (OHCA) patients attended by East Anglian Air Ambulance with arterial invasive blood pressure (IBP) measurement during chest compressions, 2015–2024of 4363 OHCA attended
- Participants
- 80 participants
- Exposure
- Intra-arrest invasive arterial BP variables vs return of spontaneous circulation (ROSC)
- Outcome
- ROSC
Methodological detailssingle air ambulance service
- Single air ambulance service
Main finding
ROSC prediction by maximum DBP
Odds ratio
1.05
95 % CI 1.03–1.08
Maximum DBP (per 1 mmHg increase)
OR 1.05 (95 % CI 1.03–1.08)
Per 1 mmHg increase, as printed
As reported in the abstract
- Maximum DBP AUC for ROSC
- 0.83 (95 % CI 0.74-0.92)
- Optimal maximum DBP cut-off
- 35 mmHg
- Sensitivity at 35 mmHg
- 94.1 %
- Specificity at 35 mmHg
- 58.7 %
Observational data: associations, not effects.
Further findings
ROSC and survival to discharge
- Achieved ROSC
- 34 (42.5 %)
- Survived to discharge
- 4 (5.0 %)
Original publication
The association between intra-arrest arterial blood pressure and return of spontaneous circulation in out-of-hospital cardiac arrest. Resuscitation. Published 6 November 2024. doi:10.
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