Cardiac arrest & resuscitation

What is the potential benefit of pre-hospital extracorporeal cardiopulmonary resuscitation for patients with an out-of-hospital cardiac arrest? A predictive modelling study

ResuscitationPublished Predictive modelling study

Authors' conclusion

Even in healthcare systems with relatively short transport distances to hospital, consideration should be given to pre-hospital initiation of ECPR for OHCA as it shortens low-flow time and increases the number of potentially eligible patients.

Study context

Population
Adults with non-traumatic out-of-hospital cardiac arrest (OHCA) attended by emergency medical services (EMS)200 (32%) eligible on EMS arrival
Participants
622 adults
Comparison
Pre-hospital vs in-hospital initiation of extracorporeal cardiopulmonary resuscitation (ECPR)
Outcome
Hypothetical number of ECPR-eligible patients as a fraction of all OHCA patients attended by EMS
Follow-up
After 10, 15 and 20 minutes of conventional CPR and upon arrival in an ECPR-centre
Methodological detailstemporal spatial analysis of Utstein data, 3 EMS, north of the Netherlands, one-year period
  • Temporal spatial analysis of Utstein data
  • 3 EMS, north of the Netherlands
  • One-year period

Main finding

As reported in the abstract

Potentially ECPR-eligible patients (no ROSC after 15 min, n = 84)
GroupValueAverage estimated low-flow time before cannulationAverage low-flow time
On-scene ECPR13.5%24 minutes
Intra-arrest transport2.5%52 minutes

Value

On-scene ECPR13.5%
Intra-arrest transport2.5%

Average estimated low-flow time before cannulation

On-scene ECPR24 minutes
Intra-arrest transport— not stated in the abstract

Average low-flow time

On-scene ECPR— not stated in the abstract
Intra-arrest transport52 minutes
Optimal transition point between conventional CPR and ECPR
15 minutes

Original publication

What is the potential benefit of pre-hospital extracorporeal cardiopulmonary resuscitation for patients with an out-of-hospital cardiac arrest? A predictive modelling study. Resuscitation. Published 11 May 2023. doi:10.1016/j.resuscitation.2023.109825

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.