Cardiac arrest & resuscitation
The association between mechanical cardiopulmonary resuscitation (CPR) and outcomes from in-hospital cardiac arrest: An observational cohort study
Authors' conclusion
Mechanical CPR was associated with a decreased likelihood of survival to hospital discharge and ROSC compared to manual CPR.
Study context
- Population
- Patients with in-hospital cardiac arrest lasting ≥5 minutes, AHA Get With The Guidelines database, 2011–2019351,125 screened
- Participants
- 111,143 patients
- Exposure
- Mechanical CPR vs manual CPR
- Outcome
- Survival to hospital discharge
Methodological detailsprospectively collected registry, 153 US institutions, multivariate logistic regression, propensity weighted analysis
- Prospectively collected registry
- 153 US institutions
- Multivariate logistic regression
- Propensity weighted analysis
Main finding
As reported in the abstract
Mechanical CPR vs Manual CPROdds ratio (95% CI)P value
Unadjusted
0.66(0.58–0.75)
P < 0.001Multivariable adjusted
0.57(0.46–0.70)
P < 0.0001- Propensity weighted
- OR 0.68 (95% CI 0.44-0 0.92); P < 0.0001
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| ROSCMultivariate adjusted | 0.68 (0.60–0.76) | P < 0.001 | |
| 0.512Odds ratio (log scale) |
Original publication
The association between mechanical CPR and outcomes from in-hospital cardiac arrest: An observational cohort study. Resuscitation. Published 10 February 2024. doi:10.
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