Cardiac arrest & resuscitation

The association of tibial vs. humeral intraosseous vascular access with patient outcomes in adult out-of-hospital cardiac arrests

ResuscitationPublished Retrospective cohort study

Authors' conclusion

We did not detect an association between the first-attempted intra-arrest IO site (tibia vs. humerus) and clinical outcomes.

Study context

Population
Adult Out-of-hospital Cardiac Arrest (OHCAs), British Columbia Cardiac Arrest registrymatched cohort n = 2052
Participants
1,404 vs 1,041
Exposure
Intraosseous (IO) tibia vs IO humerus as first-attempted vascular access
  • IO tibian = 1,404
  • IO humerusn = 1,041reference
Outcome
Favorable neurological outcome (Cerebral Performance Category 1-2) and survival at hospital discharge
Follow-up
Hospital discharge
Methodological detailsprospectively-collected registry data, propensity-matched
  • Prospectively-collected registry data
  • Propensity-matched

Main finding

As reported in the abstract

Favourable neurological outcome
IO tibia vs IO humerusOdds ratio (95% CI)
Favorable neurological outcome
1.44(0.90–2.29)
Survival to hospital discharge
1.29(0.83–2.01)

Observational data: associations, not effects.

Further findings

First-attempt success

Paramedic arrival-to-successful access interval

Original publication

The association of tibial vs. humeral intraosseous vascular access with patient outcomes in adult out-of-hospital cardiac arrests. Resuscitation. Published 3 November 2023. doi:10.1016/j.resuscitation.2023.110031

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