Hemodynamics, fluids & transfusion

The effect of peripheral vasopressor protocols on extravasation rates: A systematic review and meta-analysis

J Crit CarePublished Systematic review and meta-analysis

Pooled result · Extravasation rateResult — go to the resultU 68

Authors' conclusion

This review demonstrated that peripheral vasopressor protocols did not yield statistically significant reductions in extravasation rates among patients receiving peripheral vasopressor therapy.

Study context

Population
Critically ill adult patients (≥18 years) receiving peripherally administered vasopressors
Participants
10,983 patients · 22 studies
Comparison
Peripheral vasopressor protocol vs no protocol
Outcome
Extravasation rate (per 1000 patients)

Pooled result

Extravasation rate

U

68

P = 0.78

By group

As reported in the abstract

Original publication

The effect of peripheral vasopressor protocols on extravasation rates: A systematic review and meta-analysis. J Crit Care. Published 17 May 2026. doi:10.1016/j.jcrc.2026.155613

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