The effect of preoperative carbohydrate loading on patients’ anxiety prior to elective caesarean delivery: a randomized controlled trial
Primary result · APAIS score before surgeryResult — go to the resultMean difference −1.80 95% CI −2.35 to −1.25Authors' conclusion
Oral carbohydrate loading reduces preoperative anxiety in patients scheduled for elective caesarean delivery.
Study context
- Population
- Patients undergoing elective caesarean delivery
- Participants
- 50 vs 50
- Comparison
- Preoperative oral carbohydrate drink vs water
- Carbohydraten = 50
- Controln = 50reference
- Primary endpoint
- Preoperative anxiety (Amsterdam Preoperative Anxiety and Information Scale, Amsterdam Preoperative Anxiety and Information Scale (APAIS))
- Follow-up
- Before surgery
Primary result
APAIS score before surgery
Mean difference
−1.80
95% CI −2.35 to −1.25
P = 0.005
By group
Carbohydrate
4.56
mean · SD 1.21
Control
6.36
mean · SD 1.55
Carbohydrate vs Control
mean difference −1.80 (95% CI −2.35 to −1.25); P = 0.005
As reported in the abstract
Secondary outcomes
Hunger and thirst
- Significantly less hungry and thirsty in the carbohydrate group vs control
Urinary ketosis
- Lower incidence of urinary ketosis in the carbohydrate group vs control
Quality of recovery, first postoperative day
- Significantly higher quality of recovery in the carbohydrate group vs control
Original publication
The effect of preoperative carbohydrate loading on patients’ anxiety prior to elective caesarean delivery: a randomized controlled trial. Int J Obstet Anesth. Published 13 July 2025. doi:10.
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