Pain medicine

The impact of adverse childhood experiences on sensory thresholds in adults living with multimorbidity and chronic pain: an observational feasibility study

BJA OpenPublished Feasibility study with a cross-sectional design

Authors' conclusion

This study demonstrated that assessing sensory processing in relation to ACEs among adults with chronic pain and multimorbidity was both feasible and acceptable.

Study context

Population
Adults living with multimorbidity and chronic painof 101 approached
Participants
60 adults
Outcome
Feasibility and acceptability of the study procedures
Methodological detailssingle-site, observational
  • Single-site
  • Observational

Main finding

As reported in the abstract

Recruitment rate

59.4%

Study completion rate

100%

Protocol 'completely acceptable' (n=56)

93.3%

Protocol 'acceptable' (n=4)

6.7%

Observational data: associations, not effects.

Further findings

ACE exposure and clinical features (exploratory)

Higher ACE exposure associated with higher odds of chronic pain, multimorbidity, greater medication use, and higher pain severity and interference scores
  • Exploratory analyses

ACE count and quantitative sensory testing (QST) parameters (exploratory)

Higher ACE count linked to some mechanical static QST parameters; no relationship with dynamic QST parameters
  • Exploratory analyses

Original publication

The impact of adverse childhood experiences on sensory thresholds in adults living with multimorbidity and chronic pain: an observational feasibility study. BJA Open. Published 10 March 2026. doi:10.1016/j.bjao.2026.100545

Composed by AI from the published abstract and checked against it. How Briefs are made →

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