The impact of adverse childhood experiences on sensory thresholds in adults living with multimorbidity and chronic pain: an observational feasibility study
Authors' conclusion
This study demonstrated that assessing sensory processing in relation to ACEs among adults with chronic pain and multimorbidity was both feasible and acceptable.
Study context
- Population
- Adults living with multimorbidity and chronic painof 101 approached
- Participants
- 60 adults
- Outcome
- Feasibility and acceptability of the study procedures
Methodological detailssingle-site, observational
- Single-site
- Observational
Main finding
As reported in the abstract
Recruitment rate
59.4%
Study completion rate
100%
Protocol 'completely acceptable' (n=56)
93.3%
Protocol 'acceptable' (n=4)
6.7%
Observational data: associations, not effects.
Further findings
ACE exposure and clinical features (exploratory)
- Higher ACE exposure associated with higher odds of chronic pain, multimorbidity, greater medication use, and higher pain severity and interference scores
- Exploratory analyses
ACE count and quantitative sensory testing (QST) parameters (exploratory)
- Higher ACE count linked to some mechanical static QST parameters; no relationship with dynamic QST parameters
- Exploratory analyses
Original publication
The impact of adverse childhood experiences on sensory thresholds in adults living with multimorbidity and chronic pain: an observational feasibility study. BJA Open. Published 10 March 2026. doi:10. 1016/ j. bjao. 2026. 100545
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