What is the association between childhood adversity and subsequent chronic pain in adulthood? A systematic review
Authors' conclusion
A strong association was found between adverse childhood experiences and chronic pain in adulthood.
Study context
- Population
- Original research studies examining associations between adverse childhood experiences and chronic pain in adulthood
- Participants
- 196,130 participants · 68 studies
- Comparison
- Adverse childhood experiences and chronic pain in adulthood
- Outcome
- Association between adversity in childhood and chronic pain in adulthood
Methodological detailsprospectively registered, narrative synthesis, Most studies retrospective and of good quality, Six databases searched from January 1, 2009 until May 30, 2022
- Prospectively registered
- Narrative synthesis
- Most studies retrospective and of good quality
- Six databases searched from January 1, 2009 until May 30, 2022
Pooled result
As reported in the abstract
- Consistent associations between adverse childhood experiences and chronic pain in adulthood, with a 'dose'-dependent relationship
- Poor mental health mediated the connection between adverse childhood experiences and chronic pain
Further pooled results
Inter-rater reliability (dual reviewed papers)
- Cohen's kappa
- 0.71
Original publication
What is the association between childhood adversity and subsequent chronic pain in adulthood? A systematic review. BJA Open. Published 7 June 2023. doi:10.
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