Perioperative medicine & outcomes

The impact of frailty and rapid response team activation on patients admitted to the intensive care unit: A case‐control matched, observational, single‐centre cohort study

Acta Anaesthesiol ScandPublished Retrospective case-control study

Authors' conclusion

Frail patients admitted to ICU have a high short-term mortality. An antecedent MET event was associated with increased mortality but did not independently predict short-term survival when adjusting for confounding factors.

Study context

Population
Adults (>18 years) admitted to a medical-surgical intensive care unit (ICU)
Participants
2,314 matched admissions
Comparison
ICU admission with vs without preceding medical emergency team (MET) review; frail vs non-frail
Outcome
30-day mortality after ICU admission
Follow-up
30 days
Methodological detailssingle-centre, matched, observational
  • Single-centre
  • Matched
  • Observational

Main finding

As reported in the abstract

Mortality
Mortality in frail patients admitted after MET review
33%
Adjusted mortality HR increase per Clinical Frailty Scale (CFS) point
26%
Adjusted mortality HR increase per APACHE III point
3%

Observational data: associations, not effects.

Further findings

Limitations of medical treatment — Frail
30%
Limitations of medical treatment — Five times higher in frail vs non-frail patients, with or without MET antecedent
5

Original publication

The impact of frailty and rapid response team activation on patients admitted to the intensive care unit: A case‐control matched, observational, single‐centre cohort study. Acta Anaesthesiol Scand. Published 4 April 2024. doi:10.1111/aas.14418

Composed by AI from the published abstract and checked against it. How Briefs are made →

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