Perioperative medicine & outcomes
The impact of preoperative sleep disorders on postoperative pain and recovery in patients undergoing gastrectomy: a prospective cohort study
Authors' conclusion
In patients undergoing gastric cancer surgery, preoperative sleep disorders are associated with heightened pain sensitivity, increased postoperative opioid requirements, and prolonged hospitalization.
Study context
- Population
- Patients undergoing elective gastrectomy for gastric cancer
- Participants
- 100 patients
- Exposure
- Preoperative sleep disorder vs no sleep disorder
- Non-Sleep Disordern = 50reference
- Sleep Disordern = 50
- Outcome
- Preoperative heat pain threshold
- Follow-up
- Preoperatively
Main finding
As reported in the abstract
P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| VAS score at extubation | P < 0.001 |
| Rescue analgesia | P = 0.011 |
| Sufentanil consumption · 24 h | P = 0.042 |
| Sufentanil consumption · 48 h | P = 0.041 |
| Time to first flatus | P = 0.040 |
| Hospital LOS | P = 0.005 |
- VAS score at extubation — Higher VAS at extubation in Sleep Disorder vs Non-Sleep Disorder
- 2.60 ± 0.67 vs. 1.88 ± 0.85
- Rescue analgesia — More rescue analgesia required in Sleep Disorder vs Non-Sleep Disorder
- 38.0% vs. 14.0%
- Sufentanil consumption — More sufentanil consumed at 24 h in Sleep Disorder vs Non-Sleep Disorder (µg)
- 111.38 ± 39.24 µg vs. 97.71 ± 25.31 µg
- Sufentanil consumption — More sufentanil consumed at 48 h in Sleep Disorder vs Non-Sleep Disorder (µg)
- 190.46 ± 61.75 µg vs. 169.39 ± 36.83 µg
- Time to first flatus — Shorter time to first flatus in Sleep Disorder vs Non-Sleep Disorder (days)
- 4.48 ± 1.92 vs. 5.36 ± 2.30 days
- Hospital LOS — Significantly longer LOS in Sleep Disorder vs Non-Sleep Disorder (days)
- 8.0 vs. 7.0 days
Original publication
The impact of preoperative sleep disorders on postoperative pain and recovery in patients undergoing gastrectomy: a prospective cohort study. Perioper Med (Lond). Published 9 June 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →