Perioperative medicine & outcomes
The Impact of Psychological Prehabilitation on Surgical Outcomes: A Meta-analysis and Meta-regression
Authors' conclusion
Psychological prehabilitation reduces LOS, pain, anxiety, and depression after surgery.
Study context
- Population
- Adult surgical patients (studies with >50 patients), RCTs 2004–202420 articles
- Participants
- 2,376 patients
- Comparison
- Psychological prehabilitation vs control
- Outcome
- 4 postoperative outcomes: LOS, pain, anxiety, depression
Methodological detailsrandom effect meta-analyses, PRISMA
- Random effect meta-analyses
- PRISMA
Pooled result
As reported in the abstract
Postoperative LOS, pain, anxiety and depression (pooled)
- Greater reduction in length of stay (LOS): MD = −1.62 days; 95% CI: −2.899, −0.349; P = 0.012
- Greater reduction in pain: MD = −3.52; 95% CI: −2.642, −4.401; P < 0.001
- Greater reduction in anxiety: standard MD = −1.51; 95% CI: −0.634, −2.385; P < 0.001
- Greater reduction in depression: standard MD = −1.48; 95% CI: −0.578, −2.382; P = 0.001
- Random effect meta-analyses
Further pooled results
Meta-regression: psychotherapy modality and surgery type
- No significant effects, except for anxiety
Original publication
The Impact of Psychological Prehabilitation on Surgical Outcomes: A Meta-analysis and Meta-regression. Ann Surg. Published 19 February 2025. doi:10.
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