Cardiac arrest & resuscitation
The impact of time to defibrillation on return of spontaneous circulation in out-of-hospital cardiac arrest patients with recurrent shockable rhythms
Authors' conclusion
Every one-minute increase in intra-arrest VF/pVT duration was associated with a statistically significant 19% decrease in the chance of achieving ROSC.
Study context
- Population
- Out-of-hospital cardiac arrest (OHCA) patients with recurrent shockable rhythms (4 or 5 VF/pVT episodes), Salt Lake City Fire Department, 2012–2023622 appropriate shocks
- Exposure
- Return of spontaneous circulation (ROSC) vs no ROSC
- Outcome
- Association between VF/pVT duration preceding recurrent defibrillation and ROSC
Methodological detailsRhythm-filtering technology enabling real-time rhythm interpretation during CPR; local protocols allowing early defibrillation for recurrent/refractory VF/pVT
- Rhythm-filtering technology enabling real-time rhythm interpretation during CPR; local protocols allowing early defibrillation for recurrent/refractory VF/pVT
Main finding
As reported in the abstract
Median VF/pVT duration
P = 0.004
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| ROSC per 1-minute longer VF/pVT duration, patients with 4 VF/pVT episodes (adjusted)N = 142 · GEE regression | 0.81 (0.72–0.93) | P = 0.005 | |
| 0.512Odds ratio (log scale) |
- ROSC per 1-minute longer VF/pVT duration, patients with 4 VF/pVT episodes (adjusted) — Every 1-minute delay in intra-arrest defibrillation predicted to decrease likelihood of ROSC
- 19%
Original publication
The impact of time to defibrillation on return of spontaneous circulation in out-of-hospital cardiac arrest patients with recurrent shockable rhythms. Resuscitation. Published 18 June 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →