ICU sedation, delirium & recovery
The long-term conditional mortality rate in older ICU patients compared to the general population
Main finding · Long-term mortality in ICU patients surviving the first year vs general population (1-year landmark)Result — go to the resultHR for death 1.03 95% CI 1.02–1.04Authors' conclusion
Older ICU patients that survive the first year after an ICU admission return to a mortality rate close to that of the general population having similar baseline comorbidity, but variability is seen depending on the ICU admission diagnosis.
Study context
- Population
- Patients ≥ 55 years with a first ICU admission in the Swedish Intensive Care Registry; 7-year study period23% aged ≥80 years
- Participants
- 140,008 patients
- Exposure
- ICU vs General population
- Outcome
- Mortality beyond the first year after a first ICU admission (landmark at 1 year)
Methodological detailsage- and sex-matched general population comparison, landmark analysis at 1 year, Cox regression adjusted for age, sex and baseline comorbidity
- Age- and sex-matched general population comparison
- Landmark analysis at 1 year
- Cox regression adjusted for age, sex and baseline comorbidity
Main finding
As reported in the abstract
Long-term mortality in ICU patients surviving the first year vs general population (1-year landmark) · beyond the first year
HR for death
1.03
95% CI 1.02–1.04
ICU survivors vs General population
HR for death 1.03 (95% CI 1.02–1.04)
Observational data: associations, not effects.
Further findings
| Outcome | Estimate | |
|---|---|---|
| Mortality beyond first year, excluding cardio-thoracic ICU admissions | aHR 1.15 (95% CI 1.13–1.16) | |
| Mortality beyond first year (subgroup ≥ 75 years) | HR 0.98 (95% CI 0.96–0.99) | |
| Mortality beyond first year (subgroup acute-on-chronic respiratory failure) | aHR 1.47 (95% CI 1.36–1.58) | |
| Mortality beyond first year (subgroup other respiratory causes) | aHR 1.03 (95% CI 0.99–1.07) | |
| Mortality beyond first year (subgroup septic shock) | aHR 1.04 (95% CI 0.95–1.13) | |
| 0.512Ratio (log scale) |
Mortality beyond first year (subgroups, other admission diagnoses)
- No substantial increased mortality rate beyond the first year
Original publication
The long-term conditional mortality rate in older ICU patients compared to the general population. Crit Care. Published 14 November 2024. doi:10.
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