Perioperative medicine & outcomes
The prevalence of hyperglycemia and its association with perioperative outcomes in gynecologic surgery: a retrospective cohort study
Authors' conclusion
In our study cohort, the prevalence of hyperglycemia was low and was not associated with higher risk of composite or wound-specific complications. However, adherence to diabetes screening guidelines was poor.
Study context
- Population
- Women undergoing major gynecologic surgery on an enhanced recovery pathway, January 2018 to July 2019
- Participants
- 913 women
- Exposure
- Day-of-surgery hyperglycemia vs no hyperglycemia
- Hyperglycemicn = 67
- Outcome
- Composite and wound-specific perioperative complications
Main finding
As reported in the abstract
Perioperative complications by day-of-surgery hyperglycemia (glucose ≥ 140 g/dL)
HyperglycemiaAdjusted odds ratio (95% CI)P value
Composite perioperative complications
1.3(0.7–2.4)
P = 0.49Wound-specific complications
1.1(0.7–1.5)
P = 0.76Observational data: associations, not effects.
Further findings
Risk factors for hyperglycemia
| aOR (95% CI) | P value | ||
|---|---|---|---|
| Diabetes | 24.0 (12.3–46.9) | P < 0.001 | |
| Malignancy | 2.3 (1.2–4.5) | P = 0.01 | |
| 0.050.21520Adjusted odds ratio (log scale) |
| Outcome | Hyperglycemic |
|---|---|
| Prevalence of hyperglycemia | 7.3% |
Adherence to diabetes screening guidelines (nondiabetic patients)
- Met USPSTF criteria for diabetes screening
- 391/779 (50%)
- Documented screening in the preceding 3 years
- 117 (30%)
- Unscreened with day-of-surgery glucose ≥ 100 g/dL (suggestive of impaired glucose metabolism), of 274 unscreened
- 94 (34%)
Original publication
The prevalence of hyperglycemia and its association with perioperative outcomes in gynecologic surgery: a retrospective cohort study. Perioper Med (Lond). Published 2 June 2023. doi:10.
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