Cardiothoracic & vascular anesthesia

The Role of Other Major Postoperative Complications in Determining Outcomes of Acute Kidney Injury After Coronary Artery Bypass Surgery

Acta Anaesthesiol ScandPublished Retrospective cohort study

Main finding · MortalityResult — go to the resultHazard ratio 2.02 CI 1.10–3.70

Authors' conclusion

AKI following CABG was not associated with short- and long-term mortality in the absence of major complications but predicted a higher risk of MACCE and postoperative chronic kidney disease.

Study context

Population
Consecutive patients undergoing isolated CABG at a single nationwide center, 2001–2020, excluding preoperative dialysis
Participants
2,287 patients
Exposure
Acute kidney injury (AKI) vs No AKI
  • AKIn = 459
Outcome
Short- and long-term mortality and MACCE
Methodological detailssingle-centre, propensity score matching
  • Single-centre
  • Propensity score matching

Main finding

Mortality · 30 days

Hazard ratio

2.02

CI 1.10–3.70

AKI vs No AKI
HR 2.02 (CI 1.10–3.70)

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeHR (CI)
Long-term mortality1.46 (1.14–1.86)
Long-term MACCE1.48 (1.20–1.81)
OutcomeHR (CI)
Postoperative CKDCI as printed1.82 (2.53–2.17)

Short- and long-term mortality, excluding patients with other major complications (subgroup)

AKI not associated with short- or long-term mortality

AKI incidence and major complications

AKI (KDIGO serum creatinine criteria)
459 (20.1%)
AKI by stage (Stages 1 through 3, respectively)
375 (16.4%), 36 (1.6%), and 48 (2.1%)
Any major complication
561 (24.5%)
Both AKI and major complications
203 (8.9%)

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

The Role of Other Major Postoperative Complications in Determining Outcomes of Acute Kidney Injury After Coronary Artery Bypass Surgery. Acta Anaesthesiol Scand. Published 9 August 2025. doi:10.1111/aas.70110

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