Cardiothoracic & vascular anesthesia
The Use of Tris-hydroxymethyl Aminomethane in Patients Following Cardiac Surgery: A Retrospective Investigation
Study context
- Population
- Adults after cardiac surgery with CPB treated for postoperative metabolic acidosis, single high-volume academic centre
- Participants
- 2,066 adults
- Exposure
- Tris-hydroxymethyl aminomethane (THAM) vs sodium bicarbonate alone for postoperative metabolic acidosis
- Outcome
- pH and MAP
Methodological detailsretrospective chart review, single-centre
- Retrospective chart review
- Single-centre
Main finding
As reported in the abstract
- THAM associated with significantly higher pH and MAP vs sodium bicarbonate alone
Observational data: associations, not effects.
Secondary outcomes
- THAM not associated with AKI or mortality
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
The Use of Tris-hydroxymethyl Aminomethane in Patients Following Cardiac Surgery: A Retrospective Investigation. J Cardiothorac Vasc Anesth. Published 16 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →