Perioperative medicine & outcomes
The utility of the Ascertain Dementia Eight-item Questionnaire (AD8) and Mini-Cog in detecting cognitive impairment in older surgical patients – The Detect CI study
Authors' conclusion
Although the AD8 and Mini-Cog demonstrated comparable diagnostic accuracy for CI, the AD8 provided additional insights into preoperative patient-centered assessments and 90-day adverse outcomes.
Study context
- Population
- Non-cardiac surgical patients ≥65 years old
- Participants
- 394 patients
- Comparison
- AD8 and Mini-Cog vs Montreal Cognitive Assessment (MoCA) for detecting preoperative CI
- Outcome
- Diagnostic performance of AD8 and Mini-Cog against MoCA for preoperative CI
Performance
As reported in the abstract
Preoperative CI and diagnostic performance
Further findings
Preoperative patient-centered assessments
- CI on MoCA and AD8, but not Mini-Cog, associated with poorer preoperative patient-centered assessments
- CI on AD8 associated with poorer functional disability, frailty, anxiety and/or depression, pain, sleep quality and quality of life
Postoperative adverse outcomes by CI on AD8 (CI vs no CI); not associated for MoCA and Mini-Cog · 90 days
- All-cause complications: 15.1 % vs. 3.7 %
- P = 0.003
- ED visits: 11.3 % vs. 2.5 %
- P = 0.007
- Composite adverse outcomes: 15.1 % vs. 4.6 %
- P = 0.008
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
The utility of the Ascertain Dementia Eight-item Questionnaire (AD8) and Mini-Cog in detecting cognitive impairment in older surgical patients – The Detect CI study. J Clin Anesth. Published 21 July 2025. doi:10.
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