Using the ascertain dementia eight-item questionnaire to identify at-risk older surgical patients

doi:10.1016/j.jclinane.2026.112256

Perioperative medicine & outcomes

Using the ascertain dementia eight-item questionnaire to identify at-risk older surgical patients

J Clin AnesthPublished 4 Jun 2026Post hoc analysis of two cohort studies

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Authors' conclusion

A positive AD8 screen identified older surgical patients at risk of delirium and 90-day complications.

Study context

Population: Non-cardiac surgical patients ≥ 65 years old
Participants: 689 patients · 2 cohort studies

Comparison: Probable preoperative CI vs no CI
Primary endpoint: 30- and 90-day adverse outcomes

Primary result

As reported in the abstract

CI vs No CIAdjusted odds ratio (95% CI)P value

Delirium

3.64(1.31–9.49)

P = 0.009

90-day complications

2.26(1.14–4.28)

P = 0.015

90-day composite adverse outcomes

2.03(1.03–3.81)

P = 0.033

Further findings

AD8 item on repetition

	← Lower odds ←→ Higher odds →	aOR (95% CI)	P value
RepetitionDelirium	0.050.21520	6.11 (2.05–16.48)	P = 0.004
Repetition30-day complications	0.050.21520	2.53 (1.43–4.45)	P = 0.004
Repetition30-day composite adverse outcomes	0.050.21520	2.52 (1.44–4.46)	P = 0.004
	0.050.21520Adjusted odds ratio (log scale)

Memory-related problems

	← Lower odds ←→ Higher odds →	aOR (95% CI)	P value
Memory-related problemsDelirium	0.050.21520	5.11 (1.90–13.32)	P = 0.007
Memory-related problems30-day all-cause complications	0.050.21520	1.77 (1.11–2.79)	P = 0.044
Memory-related problems30-day composite adverse outcomes	0.050.21520	2.02 (1.30–3.14)	P = 0.008
	0.050.21520Adjusted odds ratio (log scale)

Original publication

Using the ascertain dementia eight-item questionnaire to identify at-risk older surgical patients. J Clin Anesth. Published 4 June 2026. doi:10.1016/j.jclinane.2026.112256

Read the original article ↗

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