ICU sedation, delirium & recovery
Three-year mortality of ICU survivors with sepsis, an infection or an inflammatory illness: an individually matched cohort study of ICU patients in the Netherlands from 2007 to 2019
Authors' conclusion
Both sepsis and non-sepsis infection patients had a significantly increased hazard rate of death in the 3 years after hospital discharge compared with patients with an inflammatory illness.
Study context
- Population
- Adult ICU survivors discharged alive from hospital, admitted 2007–2019 to 78 Dutch ICUs (NICE registry), classified by APACHE IV admission diagnoses78 Dutch ICUs
- Participants
- 10,000 / 10,000 / 9,997
- Exposure
- Sepsis vs Infection vs Inflammatory illness
- Sepsisn = 10,000reference
- Infectionn = 10,000
- Inflammatory illnessn = 9,997
- Outcome
- Mortality after hospital discharge
- Follow-up
- 3 years
Methodological detailsindividually matched, multicentre, registry linked to insurance claims database, sensitivity analyses
- Individually matched
- Multicentre
- Registry linked to insurance claims database
- Sensitivity analyses
Main finding
As reported in the abstract
Three-year mortality after discharge
Each group vs sepsisAdjusted hazard ratio (95% CI)
Infection
1.00(0.95–1.05)
Inflammatory illness
0.88(0.83–0.94)
Observational data: associations, not effects.
Original publication
Three-year mortality of ICU survivors with sepsis, an infection or an inflammatory illness: an individually matched cohort study of ICU patients in the Netherlands from 2007 to 2019. Crit Care. Published 19 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →