Pediatric anesthesia & critical care

Thrombotic Complications Associated With Right Atrial Lines in Neonates and Infants Undergoing Cardiac Surgery. Is Calcium Chloride a Culprit?

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Main finding · Thrombotic eventsResult — go to the resultOdds ratio 3.46 95% CI 1.02–11.7

Authors' conclusion

In this single-center study, a significant decrease in the odds of an atrial catheter-related thrombus when a calcium gluconate infusion is used instead of calcium chloride was shown.

Study context

Population
Neonates undergoing cardiac surgery with a central venous catheter or tunneled atrial catheter, single centre in Houston, TXprocedures in 135 patients
Participants
181 neonates
Exposure
Calcium chloride vs Calcium gluconate
  • Calcium chloriden = 93 procedures
  • Calcium gluconaten = 88 proceduresreference
Outcome
Thrombotic events
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Odds ratio

3.46

95% CI 1.02–11.7

P = 0.047

By group

Calcium chloride vs Calcium gluconate
OR 3.46 (95% CI 1.02–11.7); P = 0.047
Overall incidence of thrombosis
9.9%

Observational data: associations, not effects.

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Thrombotic Complications Associated With Right Atrial Lines in Neonates and Infants Undergoing Cardiac Surgery. Is Calcium Chloride a Culprit? J Cardiothorac Vasc Anesth. Published 13 January 2025. doi:10.1053/j.jvca.2025.01.008

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