Pediatric anesthesia & critical care
Thrombotic Complications Associated With Right Atrial Lines in Neonates and Infants Undergoing Cardiac Surgery. Is Calcium Chloride a Culprit?
Main finding · Thrombotic eventsResult — go to the resultOdds ratio 3.46 95% CI 1.02–11.7Authors' conclusion
In this single-center study, a significant decrease in the odds of an atrial catheter-related thrombus when a calcium gluconate infusion is used instead of calcium chloride was shown.
Study context
- Population
- Neonates undergoing cardiac surgery with a central venous catheter or tunneled atrial catheter, single centre in Houston, TXprocedures in 135 patients
- Participants
- 181 neonates
- Exposure
- Calcium chloride vs Calcium gluconate
- Calcium chloriden = 93 procedures
- Calcium gluconaten = 88 proceduresreference
- Outcome
- Thrombotic events
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Odds ratio
3.46
95% CI 1.02–11.7
P = 0.047
By group
Calcium chloride vs Calcium gluconate
OR 3.46 (95% CI 1.02–11.7); P = 0.047
- Overall incidence of thrombosis
- 9.9%
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Thrombotic Complications Associated With Right Atrial Lines in Neonates and Infants Undergoing Cardiac Surgery. Is Calcium Chloride a Culprit? J Cardiothorac Vasc Anesth. Published 13 January 2025. doi:10. 1053/ j. jvca. 2025. 01. 008
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