Towards personalized medicine: a scoping review of immunotherapy in sepsis
Authors' conclusion
When a personalized approach was applied, trends of clinical benefit for several interventions emerged, which hold promise for future clinical trials using personalized immunotherapy.
Study context
- Population
- Adults with sepsis in RCTs and cohort studies of immunomodulatory therapiesstudies included
- Participants
- 771 adults
- Outcome
- Studies of immunotherapy in adult sepsis included, and those incorporating a personalized immunotherapy approach
Methodological details15,853 studies found; 1409 (9%) assessed for eligibility, Searched PubMed, Embase, Cochrane CENTRAL and ClinicalTrials.gov to January 29th, 2024
- 15,853 studies found; 1409 (9%) assessed for eligibility
- Searched PubMed, Embase, Cochrane CENTRAL and ClinicalTrials.gov to January 29th, 2024
Main finding
As reported in the abstract
Studies included
771
Observational studies
282
37%
Interventional studies
489
63%
Studies incorporating a personalized approach
70
9%
Original publication
Towards personalized medicine: a scoping review of immunotherapy in sepsis. Crit Care. Published 28 May 2024. doi:10.
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