Perioperative medicine & outcomes

Towards reliable prediction of intraoperative hypotension: a cross-center evaluation of deep learning-based and MAP-derived methods

J Clin Monit ComputPublished Retrospective cross-center model evaluation study

Study context

Population
Surgical patients, Karolinska University Hospital (Sweden) and VitalDB (Korea) datasets
Exposure
Deep learning (AI) model vs MAP threshold method for predicting intraoperative hypotension
Outcome
Prediction of intraoperative hypotension
Methodological detailsmulticentre, cross-validation, cross-age validation
  • Multicentre
  • Cross-validation
  • Cross-age validation

Main finding

As reported in the abstract

  • AI model performs better than MAP threshold in more ambiguous (Gray Zone, MAP 65-75 mmHg) cases
  • With clearly separated MAP values between classes, both methods performed similarly well

Observational data: associations, not effects.

Further findings

Cross-dataset generalizability

Models trained on datasets with more Gray Zone cases generalized better to datasets with clearer class separation; the reverse struggled
Standardizing MAP difference between positive and negative samples virtually eliminated class separation; inflated performance attributable to selection bias

Cross-age and ASA validation

Models trained on older patients generalized better to younger cohorts
Differences in ASA classification had minimal effect

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Towards reliable prediction of intraoperative hypotension: a cross-center evaluation of deep learning-based and MAP-derived methods. J Clin Monit Comput. Published 12 September 2025. doi:10.1007/s10877-025-01357-0

Composed by AI from the published abstract and checked against it. How Briefs are made →

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