Hemodynamics, fluids & transfusion
Hypotension Prediction Index Is Equally Effective in Predicting Intraoperative Hypotension during Noncardiac Surgery Compared to a Mean Arterial Pressure Threshold: A Prospective Observational Study
Authors' conclusion
In clinical practice, the Hypotension Prediction Index alarms are highly similar to those derived from mean arterial pressure, which implies that the machine learning algorithm could be substituted by an alarm based on a mean arterial pressure threshold set at 72 or 73 mmHg.
Study context
- Population
- Patients undergoing moderate- to high-risk elective noncardiac surgery
- Participants
- 100 patients
- Exposure
- Hypotension Prediction Index vs MAP-based prediction methods
- Outcome
- Predictive performance for intraoperative hypotension (AUC) of HPI vs MAP-based methods
- Follow-up
- Within 5 min before hypotension
Main finding
As reported in the abstract
AUC for predicting hypotension within 5 min · within 5 min
HPI
0.89
CI 0.88–0.89
Concurrent MAP
0.88
CI 0.88–0.89
Linearly extrapolated MAP
0.85
CI 0.84–0.85
Delta MAP
0.66
CI 0.65–0.67
Observational data: associations, not effects.
Further findings
PPV
Agreement in time with default HPI alarm
- MAP threshold of 73 mmHg agreed with default HPI alarm
- 97%
- MAP threshold of 72 mmHg had most comparable predictive performance
Original publication
Hypotension Prediction Index Is Equally Effective in Predicting Intraoperative Hypotension during Noncardiac Surgery Compared to a Mean Arterial Pressure Threshold: A Prospective Observational Study. Anesthesiology. Published 1 April 2024. doi:10. 1097/ aln. 0000000000004990
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