Hemodynamics, fluids & transfusion

Hypotension Prediction Index Is Equally Effective in Predicting Intraoperative Hypotension during Noncardiac Surgery Compared to a Mean Arterial Pressure Threshold: A Prospective Observational Study

AnesthesiologyPublished Prospective observational study

Authors' conclusion

In clinical practice, the Hypotension Prediction Index alarms are highly similar to those derived from mean arterial pressure, which implies that the machine learning algorithm could be substituted by an alarm based on a mean arterial pressure threshold set at 72 or 73 mmHg.

Study context

Population
Patients undergoing moderate- to high-risk elective noncardiac surgery
Participants
100 patients
Exposure
Hypotension Prediction Index vs MAP-based prediction methods
Outcome
Predictive performance for intraoperative hypotension (AUC) of HPI vs MAP-based methods
Follow-up
Within 5 min before hypotension

Main finding

As reported in the abstract

AUC for predicting hypotension within 5 min · within 5 min

HPI

0.89

CI 0.88–0.89

Concurrent MAP

0.88

CI 0.88–0.89

Linearly extrapolated MAP

0.85

CI 0.84–0.85

Delta MAP

0.66

CI 0.65–0.67

Observational data: associations, not effects.

Further findings

PPV

Agreement in time with default HPI alarm

MAP threshold of 73 mmHg agreed with default HPI alarm
97%
MAP threshold of 72 mmHg had most comparable predictive performance

Original publication

Hypotension Prediction Index Is Equally Effective in Predicting Intraoperative Hypotension during Noncardiac Surgery Compared to a Mean Arterial Pressure Threshold: A Prospective Observational Study. Anesthesiology. Published 1 April 2024. doi:10.1097/aln.0000000000004990

Composed by AI from the published abstract and checked against it. How Briefs are made →

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