Traditional Chinese medicine for sepsis: advancing from evidence to innovative drug discovery
Study context
- Population
- Patients with sepsis
Main finding
As reported in the abstract
- Most Traditional Chinese medicine (TCM) preparations evaluated for sepsis lack robust clinical evidence
- Xuebijing Injection showed efficacy in a large multicentre, randomised, double-blind, placebo-controlled trial
- Evidence for Shenfu and Shenmai Injections comes mainly from smaller single-centre studies with significant methodological limitations
Further findings
Bioactive compounds from TCM
- Pharmacological effects and mechanisms of some compounds elucidated, suggesting potential for TCM-based anti-sepsis drug discovery
Original publication
Traditional Chinese medicine for sepsis: advancing from evidence to innovative drug discovery. Crit Care. Published 15 May 2025. doi:10. 1186/ s13054-025-05441-4
Composed by AI from the published abstract and checked against it. How Briefs are made →