Perioperative medicine & outcomes
Trail making test B in postoperative delirium: a replication study
Authors' conclusion
The TMT-B was associated with postoperative delirium, but its predictive performance as a stand-alone test was low.
Study context
- Population
- Older adults (≥65 yr) scheduled for major surgery without signs of dementia
- Participants
- 841 adults
- Exposure
- Preoperative Trail Making Test B (TMT-B) score and postoperative delirium
- Outcome
- Association of preoperative TMT-B results with postoperative delirium (assessed twice daily)
Methodological detailslongitudinal observational, binational, two-centre, replication study
- Longitudinal observational
- Binational
- Two-centre
- Replication study
Main finding
As reported in the abstract
Postoperative delirium
Incidence of postoperative delirium
151
18%
OR per 10-s TMT-B increment (95% CI 1.02-1.09), P=0.001
1.06
AUC (95% CI 0.55-0.64), P<0.001
0.60
Observational data: associations, not effects.
Further findings
Postoperative delirium after removing 21 outliers (sensitivity analysis)
- OR per 10-s increment (95% CI 1.03-1.07), P<0.001
- 1.07
Postoperative delirium with impaired or missing TMT-B data (n=88)
- OR (95% CI 1.71-4.35), P<0.001
- 2.74
Original publication
Trail making test B in postoperative delirium: a replication study. BJA Open. Published 3 November 2023. doi:10.
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