Trajectories of post-traumatic stress in sepsis survivors two years after ICU discharge: a secondary analysis of a randomized controlled trial
Authors' conclusion
Post-traumatic stress is a relevant long-term burden for sepsis patients after ICU stay.
Study context
- Population
- Sepsis survivors after ICU dischargeall follow-ups completed
- Participants
- 175 survivors
- Comparison
- Trajectories of post-traumatic stress symptoms (Post-traumatic Symptom Scale (PTSS-10)) up to 24 months after ICU discharge
- Stable low symptomsn = 104
- Increasing symptomsn = 45
- Recovering from symptomsn = 26
- Primary endpoint
- Clinical trajectories of post-traumatic stress symptoms (PTSS-10)
- Follow-up
- 24 months
Methodological detailsk-means clustering, multinomial log-linear models
- K-means clustering
- Multinomial log-linear models
Primary result
As reported in the abstract
Trajectory clusters of PTSS levels
Further findings
Predictor of decrease: initially high post-traumatic symptoms
| OR (95% CI) | ||
|---|---|---|
| Initially high post-traumatic symptomsMore likely to show a decrease | 1.1 (1.05–1.16) | |
| 0.512Odds ratio (log scale) |
Predictor of increasing PTSS levels: female sex
| OR (CI) | ||
|---|---|---|
| Females | 2.45 (1.11–5.41) | |
| 0.20.5125Odds ratio (log scale) |
Predictor of increasing PTSS levels: early traumatic memories of the ICU
| OR (CI) | ||
|---|---|---|
| Early traumatic memories of the ICU | 4.04 (1.63–10) | |
| 0.10.31310Odds ratio (log scale) |
Original publication
Trajectories of post-traumatic stress in sepsis survivors two years after ICU discharge: a secondary analysis of a randomized controlled trial. Crit Care. Published 29 January 2024. doi:10.
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