Hemodynamics, fluids & transfusion
Transfusion-free Strategies in Liver and Pancreatic Surgery: A Predictive Model of Blood Conservation for Transfusion Avoidance in Mainstream Populations
Authors' conclusion
Deliberate perioperative management makes transfusion-free liver and pancreatic resections feasible.
Study context
- Population
- Jehovah Witness patients undergoing liver and pancreatic resections
- Participants
- 101 major resections
- Exposure
- Liver vs Pancreas
- Livern = 57
- Pancreasn = 44
- Outcome
- Perioperative outcomes of transfusion-free liver and pancreatic resections
Methodological detailssingle-centre, 23-year review
- Single-centre
- 23-year review
Main finding
As reported in the abstract
Clavien grade ≥3 morbidity
Observational data: associations, not effects.
Further findings
Events
| Outcome | Liver | Pancreas |
|---|---|---|
| Use of acute normovolemic hemodilution (ANH) | 38 | 34 |
- Use of acute normovolemic hemodilution (ANH) — ANH utilized, total patients
- 72
- Use of acute normovolemic hemodilution (ANH) — Median units removed, returned for hemorrhage or at end of operation
- 2
Original publication
Transfusion-free Strategies in Liver and Pancreatic Surgery: A Predictive Model of Blood Conservation for Transfusion Avoidance in Mainstream Populations. Ann Surg. Published 17 November 2022. doi:10. 1097/ sla. 0000000000005757
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