Pediatric anesthesia & critical care
Transition to Weight-Based High-Flow Nasal Cannula Use Outside of the Intensive Care Unit (ICU) for Bronchiolitis
Main finding · ICU admissionResult — go to the resultDecrease per year 6.1% 95% CI 8.7%–3.4%Authors' conclusion
Results of this cohort study of hospitalized patients with bronchiolitis suggest that transition from ICU-only to weight-based non-ICU HFNC protocols is associated with reduced ICU admission rates.
Study context
- Population
- Patients aged 0 to 24 months hospitalised with bronchiolitis at 18 US children's hospitals (Pediatric Health Information Systems), 2010–2021
- Participants
- 86,046 patients · 18 hospitals
- Exposure
- Weight-based protocol vs ICU-only
- Weight-based protocoln = 38,710
- ICU-onlyn = 47,336reference
- Outcome
- Proportion of patients with bronchiolitis admitted to the ICU
Methodological detailsmulticentre, controlled interrupted time series
- Multicentre
- Controlled interrupted time series
Main finding
ICU admission
Decrease per year
6.1%
95% CI 8.7%–3.4%
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Reduction per year (95% CI) |
|---|---|
| Noninvasive positive pressure ventilation use | 1.5% (2.8%–0.1%) |
Mean LOS and invasive mechanical ventilation
- No differences between groups
Original publication
Transition to Weight-Based High-Flow Nasal Cannula Use Outside of the ICU for Bronchiolitis. JAMA Netw Open. Published 4 March 2024. doi:10.
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