Perioperative medicine & outcomes
Treatment of iron deficiency in patients scheduled for pancreatic surgery: implications for daily prehabilitation practice in pancreatic surgery
Authors' conclusion
ID is prevalent in patients scheduled for pancreatic surgery and is amendable to preoperative correction. Preoperative IVIS increased Hb levels effectively and reduced postoperative SSI.
Study context
- Population
- Patients scheduled for pancreatic surgery referred to an outpatient prehabilitation clinic, University Medical Center Groningen, the Netherlands, May 2019–August 2022screened
- Participants
- 164 patients
- Exposure
- Preoperative IV iron supplementation vs standard care
- Intravenous iron supplementation (IVIS)n = 25
- Outcome
- Preoperative anemia and ID prevalence
Methodological detailssingle-centre, longitudinal
- Single-centre
- Longitudinal
Main finding
As reported in the abstract
Preoperative anemia
55
33.5%
Iron deficiency (ID) as underlying cause of anemia
23
41.8%
ID without concomitant anemia
21
Patients with ID
44
Observational data: associations, not effects.
Further findings
Mean Hb at outpatient clinic
P < 0.001
Mean Hb one day prior to surgery
P < 0.001
Mean Hb at discharge
P = 0.13
SSI
P = 0.02
| Outcome | OR (CI) | P value | |
|---|---|---|---|
| SSIMultivariable regression analysis | 7.01 (1.68–49.75) | P = 0.02 | |
| 0.050.21520Odds ratio (log scale) |
Change in mean hemoglobin (Hb) with preoperative IVIS (IVIS)
- Significant increase in mean Hb from 10.8 to 11.8 g/dL, p = 0.03
Original publication
Treatment of iron deficiency in patients scheduled for pancreatic surgery: implications for daily prehabilitation practice in pancreatic surgery. Perioper Med (Lond). Published 11 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →