Perioperative medicine & outcomes

Two Weeks Versus One Week of Maximal Patient-Intensivist Continuity for Adult Medical Intensive Care Patients: A Two-Center Target Trial Emulation*

Crit Care MedPublished Retrospective cohort study

Authors' conclusion

Two weeks of maximal patient-intensivist continuity was not associated with differences in clinical outcomes compared with 1 week in two medical ICUs.

Study context

Population
Adults (≥18 y) admitted to two US urban teaching medical ICUs with 2-week intensivist service blocks, March 2017–February 2020
Participants
2,571 adults
Exposure
Admission during intensivist's first week vs second week
  • 2 weeksn = 1,254
  • 1 weekn = 1,317reference
Outcome
Hospital mortality and ICU LOS
Methodological detailstarget trial emulation, inverse probability weighting, two-centre
  • Target trial emulation
  • Inverse probability weighting
  • Two-centre

Main finding

As reported in the abstract

2 weeks vs 1 weekOdds ratio (95% CI)
Adjusted mortality
1.01(0.96–1.06)
2 weeks vs 1 weekDifference, d (95% CI)
ICU LOS
−0.25(−0.82 d to +0.32 d)

Observational data: associations, not effects.

Further findings

OutcomeOR (CI)
Mechanically ventilated patients (subgroup): mortality, ICU LOS, duration of ventilation2 weeks vs 1 week · adjusted mortality1.00 (0.87–1.16)
OutcomeDifference (d) (CI)
Mechanically ventilated patients (subgroup): mortality, ICU LOS, duration of ventilation2 weeks vs 1 week · ICU LOS+0.06 (−0.78 d to +0.91 d)
Mechanically ventilated patients (subgroup): mortality, ICU LOS, duration of ventilation2 weeks vs 1 week · duration of mechanical ventilation+0.37 (−0.46 d to +1.21 d)

Mechanically ventilated patients (subgroup): mortality, ICU LOS, duration of ventilation

No differences

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Two Weeks Versus One Week of Maximal Patient-Intensivist Continuity for Adult Medical Intensive Care Patients: A Two-Center Target Trial Emulation*. Crit Care Med. Published 7 May 2024. doi:10.1097/ccm.0000000000006322

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