Ultrasound assessment of muscle mass in critically ill patients: A correlation with nutritional support and clinical outcomes
Authors' conclusion
Our study demonstrates that critically ill patients experience significant muscle mass loss within the first 72 h of ICU. QMLT reduction significantly impacts 28-day mortality, with an 8.8 % increase in the odds of death per 0.1 cm reduction.
Study context
- Population
- Critically ill Intensive Care Unit (ICU) patientsincluded in the analysis
- Participants
- 128 patients
- Outcome
- Relationship between ultrasound quadriceps muscle measures (RFCSA, QMLT), nutritional support and clinical outcomes
Methodological detailssingle tertiary centre, three ICUs
- Single tertiary centre
- Three ICUs
Main finding
As reported in the abstract
Quadriceps muscle loss on ultrasound · days 3 and 7
QMLT decrease, days 3 and 7
5 % and 13 %
RFCSA decrease, days 3 and 7
10 % and 27 %
Observational data: associations, not effects.
Further findings
| Outcome | aOR (95 % CI) | P value | |
|---|---|---|---|
| 28-day mortality by QMLT reduction (multivariate logistic regression) · per 0.1 cm reduction | 1.088 (1.018–1.113) | P = 0.015 | |
| 0.512Adjusted odds ratio (log scale) |
Daily caloric and protein intake, non-survivors vs survivors
- Lower daily caloric and protein intake in non-survivors
- P < 0.001
Original publication
Ultrasound assessment of muscle mass in critically ill patients: A correlation with nutritional support and clinical outcomes. J Crit Care. Published 19 October 2024. doi:10.
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