Urine output is an early and strong predictor of acute kidney injury and associated mortality: a systematic literature review of 50 clinical studies
Authors' conclusion
Evidence suggests that the inclusion of UO criteria provides substantial diagnostic and prognostic value to the detection of AKI.
Study context
- Population
- Studies evaluating both urine output (UO) and serum creatinine (SC) in the detection of acute kidney injury (AKI)50 studies
- Comparison
- Urine output vs serum creatinine criteria for AKI detection
- Outcome
- Incidence of AKI
Methodological detailsPRISMA, 76% of studies used KDIGO criteria
- PRISMA
- 76% of studies used KDIGO criteria
Main finding
As reported in the abstract
Further findings
Time to AKI diagnosis
- Earlier diagnosis of AKI with UO criteria
- 2.4-46.0 h
AKI-related mortality
- Both diagnostic modalities accurately predicted risk of AKI-related mortality
Original publication
Urine output is an early and strong predictor of acute kidney injury and associated mortality: a systematic literature review of 50 clinical studies. Ann Intensive Care. Published 9 July 2024. doi:10.
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