Cardiothoracic & vascular anesthesia
Continuous Urine Output-Based Alert Identifies Cardiac Surgery–associated Acute Kidney Injury Earlier Than Serum Creatinine: A Prospective and Retrospective Observational Study
Main finding · AKI diagnosis by stage and timingResult — go to the resultTime to diagnosis earlier (UO stage ≥1 vs SCr stage ≥2) 33.6 hoursAuthors' conclusion
AKI Alert, based on continuous UO and enabled by active drain line clearance, detected AKI stages 1 and 2 before SCr criteria.
Study context
- Population
- Cardiac surgery patients, 9 tertiary centresanalysed
- Participants
- 522 patients
- Exposure
- Continuous urine output (UO)-based acute kidney injury (AKI) Alert vs serum creatinine (SCr) criteria
- Outcome
- AKI diagnosis by stage and timing
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Time to diagnosis earlier (UO stage ≥1 vs SCr stage ≥2)
33.6 hours
By group
UO
32.18%, 30.46%, 3.64%
AKI stages 1, 2, 3
SCr
33.72%, 4.60%, 3.26%
AKI stages 1, 2, 3
Observational data: associations, not effects.
Further findings
Associations of AKI Alert with outcomes
- Stage 1 alert significantly associated with increased ICU and hospital LOS and CRRT
- Stage ≥2 alerts associated with mortality
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Continuous Urine Output-Based Alert Identifies Cardiac Surgery–associated Acute Kidney Injury Earlier Than Serum Creatinine: A Prospective and Retrospective Observational Study. J Cardiothorac Vasc Anesth. Published 19 June 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →