Cardiothoracic & vascular anesthesia
The use of transcutaneous electrical acupoint stimulation to reduce opioid consumption in patients undergoing off-pump CABG: a randomized controlled trial
Authors' conclusion
Transcutaneous electrical acupoint stimulation with distal-proximal acupoints combination, compared to regional acupoints combination and sham acupuncture, significantly reduced sufentanil consumption in patients who underwent off-pump coronary artery bypass grafting surgery.
Study context
- Population
- Patients undergoing off-pump CABG under GA313 completed
- Participants
- 315 patients
- Comparison
- Transcutaneous electrical acupoint stimulation (TEAS) with distal-proximal or regional acupoints combination vs sham acupuncture, 30 min before anaesthesia induction
- Sham acupuncturen = 105reference
- Regional acupoints combinationn = 105
- Distal-proximal acupoints combinationn = 105
- Primary endpoint
- Sufentanil dose during anaesthesia
Methodological detailsmulticentre, double-blind, sham-controlled
- Multicentre
- Double-blind
- Sham-controlled
Primary result
As reported in the abstract
Mean difference
- 34.9 μg
CI - 64.9 to - 4.9P = 0.023
Distal-proximal vs Sham
Mean difference
- 35.5 μg
CI - 65.6 to - 5.5P = 0.020
Distal-proximal vs Regional
Distal-proximal
303.9
unspecified (as printed in parentheses) 10.8 · μg
Regional
339.5
Secondary outcomes
Secondary outcomes (vasoactive-inotropic score, propofol consumption, mechanical ventilation, cardiac care unit and postoperative hospital stay, complications, 30-day mortality)
- Comparable among three groups
Original publication
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