Utilization and outcomes of life-supporting interventions in older ICU patients in Japan: a nationwide registry study
Authors' conclusion
Although life-supporting interventions tended to decrease with age, a considerable number of patients of advanced age still received these interventions.
Study context
- Population
- Adults admitted to ICUs in the Japanese Intensive Care Patient Database (JIPAD), April 1, 2015, to March 31, 20226 age groups
- Participants
- 233,093 adults
- Exposure
- 18-59 vs 80s vs 90-99 vs 100s
- 90-99n = 5,303
- 100sn = 67
- Outcome
- Proportion receiving a composite of:
- Mechanical ventilation
- Continuous renal replacement therapy
- Veno-venous or veno-arterial ECMO
Methodological detailsretrospective, multicentre registry
- Retrospective
- Multicentre registry
Main finding
As reported in the abstract
Composite life-supporting interventions
Observational data: associations, not effects.
Further findings
Non-invasive ventilation (NIV) use
- NIV use increased with age; consistent proportion receiving either NIV or mechanical ventilation until their 90s
Mortality, age ≥80 years
- ICU mortality
- 5.6%
- Hospital mortality
- 12.9%
Not returning home
- Patients in their 80s
- Approximately half
- Patients older than 90 years
- 60%
Age distribution
- Median age
- 71 years
- Patients in their 80s
- 18.2%
- Patients in their 90s
- 2.3%
Original publication
Utilization and outcomes of life-supporting interventions in older ICU patients in Japan: a nationwide registry study. Intensive Care Med. Published 7 January 2025. doi:10.
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