ICU sedation, delirium & recovery

Validation of PRE‐DELIRIC and E‐PRE‐DELIRIC in a Danish population of intensive care unit patients—A prospective observational multicenter study

Acta Anaesthesiol ScandPublished Diagnostic accuracy study

Authors' conclusion

In a Danish cohort, we found that the PRE-DELIRIC model demonstrated acceptable performance and E-PRE-DELIRIC demonstrated poor performance.

Study context

Population
Adults acutely admitted for >24 h to four general intensive care unit (ICUs), Zealand Region of Denmark, January 2022 to January 2023
Comparison
PRE-DELIRIC vs E-PRE-DELIRIC delirium prediction models
Outcome
Prognostic accuracy (AUROC) and calibration plot for delirium (CAM-ICU) throughout ICU stay
Methodological detailsprospective, observational, multicentre, external validation
  • Prospective
  • Observational
  • Multicentre
  • External validation

Performance

As reported in the abstract

Test or modelArea Under the Receiver Operating Characteristics (AUROC)Calibration
PRE-DELIRIC0.70 (95% CI 0.66 to 0.74)good
E-PRE-DELIRIC0.63 (95% CI 0.58 to 0.67)poor

Area Under the Receiver Operating Characteristics (AUROC)

PRE-DELIRIC0.70 (95% CI 0.66 to 0.74)
E-PRE-DELIRIC0.63 (95% CI 0.58 to 0.67)

Calibration

PRE-DELIRICgood
E-PRE-DELIRICpoor

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Validation of PRE‐DELIRIC and E‐PRE‐DELIRIC in a Danish population of intensive care unit patients—A prospective observational multicenter study. Acta Anaesthesiol Scand. Published 27 November 2023. doi:10.1111/aas.14363

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