ICU sedation, delirium & recovery
Validation of the patient State Index for monitoring sedation state in critically ill patients: a prospective observational study
Authors' conclusion
The PSI correlated positively with RASS scores, which represented a widely used tool for assessing sedation levels, and the values were significantly different among RASS scores. Additionally, the PSI had a high sensitivity and specificity for distinguishing light from deep sedation.
Study context
- Population
- Mechanically ventilated intensive care unit (ICU) patients382 Patient State Index (PSI)–Richmond Agitation-Sedation Scale (RASS) sets
- Participants
- 50 participants
- Exposure
- PSI vs RASS score
- Outcome
- Correlation between PSI and RASS score
Methodological detailsblinded to PSI values
- Blinded to PSI values
Main finding
As reported in the abstract
Correlation between PSI and RASS
- Spearman's rank correlation coefficient, PSI vs RASS
- 0.79 (95% CI 0.75-0.83)
- PSI differed significantly among RASS scores (Kruskal-Wallis chi-square 242, df = 6)
- P < 2.2-e16
Observational data: associations, not effects.
Further findings
PSI threshold distinguishing light (RASS ≥ - 2) from deep (RASS ≤ - 3) sedation
- PSI threshold
- 54 (95% CI 50-65)
- AUC
- 0.92 (95% CI 0.89-0.95)
- Sensitivity
- 0.91 (95% CI 0.86-0.95)
- Specificity
- 0.81 (95% CI 0.77-0.86)
Original publication
Validation of the patient State Index for monitoring sedation state in critically ill patients: a prospective observational study. J Clin Monit Comput. Published 4 June 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →