Evaluation of patient state index, bispectral index, and entropy during drug induced sleep endoscopy with dexmedetomidine
Authors' conclusion
Commercial EEG monitors can capture changes in the brain state associated with the RASS score during dexmedetomidine sedation.
Study context
- Population
- Patients undergoing drug induced sleep endoscopy with dexmedetomidine sedation
- Participants
- 51 patients
- Exposure
- Patient state index (PSI) vs BIS vs Entropy vs SEF95
- Outcome
- Association of EEG markers with RASS score (ordinal logistic regression)
Methodological detailsplayback system extraction from continuous EEG
- Playback system extraction from continuous EEG
Main finding
As reported in the abstract
Association with RASS score
- PSI, BIS and Entropy each significantly associated with Richmond Agitation-Sedation Scale (RASS) score
- p < 0.001 for all metrics
Observational data: associations, not effects.
Further findings
| Outcome | PSI | BIS | Entropy |
|---|---|---|---|
| Accuracy predicting deeper levels of sedation | 58.3% | 44.4% | 58.3% |
Lightening secondary to RASS score assessment
- Significantly captured by PSI, BIS and Entropy
- P < 0.001
Original publication
Evaluation of patient state index, bispectral index, and entropy during drug induced sleep endoscopy with dexmedetomidine. J Clin Monit Comput. Published 22 December 2022. doi:10.
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