Cardiac arrest & resuscitation
Vasopressor or advanced airway first in cardiac arrest?
Authors' conclusion
Vasopressor-airway resuscitation sequence was not associated with OHCA outcomes or CPR quality.
Study context
- Population
- Out-of-hospital Cardiac Arrest (OHCA) patients in the Pragmatic Airway Resuscitation Trial (PART)of 3,004 in parent trial
- Participants
- 2,404 patients
- Comparison
- Vasopressor-first vs advanced airway-first resuscitation sequence
- Vasopressor-firstn = 1,821
- Advanced airway-firstn = 583reference
Primary result
As reported in the abstract
OHCA outcomes
Vasopressor-first vs Advanced airway-firstAdjusted odds ratio (95% CI)
72-hour survival
0.96(0.71–1.31)
ROSC
0.83(0.66–1.06)
Hospital survival
1.09(0.68–1.73)
Hospital survival with favorable neurologic status
0.97(0.53–1.78)
Further findings
CPR outside recommended parameters
- Vasopressor-first not associated with non-compliance with recommended CPR performance parameters
Intervention times from ALS arrival
- ALS arrival-to-vasopressor, median 8 min (IQR 6-11)
- 8
- ALS arrival-to-airway, median 11 min (8-15)
- 11
Original publication
Vasopressor or advanced airway first in cardiac arrest? Resuscitation. Published 30 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →