Venous congestion in septic shock quantified with point-of-care ultrasound: a pilot prospective multicentre cohort study
Authors' conclusion
It is feasible to conduct a definitive observational study exploring the association between venous congestion quantified with POCUS and clinical outcomes in patients with septic shock.
Study context
- Population
- Adults with septic shock recruited within 12 hr of ICU admission
- Participants
- 75 adults
- Outcome
- Successful completion rate of the two VEXUS scores (day 1 and day 3 of ICU admission)
Methodological detailspilot, multicentre, two intensive care units (ICUs), January 2022 to January 2023
- Pilot
- Multicentre
- Two ICUs
- January 2022 to January 2023
Main finding
As reported in the abstract
Success rate of completion for VEXUS scans
Success rate of completion for Venous Excess Ultrasound Score (VEXUS) scans
94.5%
95% CI 89.5 to 97.6
Observational data: associations, not effects.
Further findings
Renal replacement therapy (RRT), venous congestion on ICU admission
| Unadjusted HR (95% CI) | P value | ||
|---|---|---|---|
| Venous congestion on ICU admissionMay be associated with a higher risk of requiring RRT | 3.35 (0.94–11.88) | P = 0.06 | |
| 0.050.21520Unadjusted hazard ratio (log scale) |
Severe venous congestion, ICU admission day 1
- Severe venous congestion (14/75)
- 19%
Severe venous congestion, day 3
- Severe venous congestion (10/61)
- 16%
Original publication
Venous congestion in septic shock quantified with point-of-care ultrasound: a pilot prospective multicentre cohort study. Can J Anaesth. Published 28 March 2024. doi:10.
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