Organ support & nutrition

What Factors Are Associated With Arterial Line–Related Limb Ischemia in Patients on Extracorporeal Membrane Oxygenation? A Single-Center Retrospective Cohort Study

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Authors' conclusion

Arterial line-related limb ischemia is much more common in ECMO patients than in the typical intensive care unit setting. The SOFA score may be useful in identifying which patients may be at risk for arterial line-related limb ischemia.

Study context

Population
Consecutive patients treated with extracorporeal membrane oxygenation (ECMO) over 6 years at a single academic tertiary referral ECMO center
Participants
278 consecutive ECMO patients
Outcome
Factors associated with arterial line-related limb ischemia
Follow-up
During the ECMO run
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Arterial line-related limb ischemia: incidence and independent associations

Arterial line-related limb ischemia, n (%)

19

7%

Postcannulation Sequential Organ Failure Assessment (SOFA), aOR

1.20 (1.08-1.32) (95% CI)

APACHE-II, aOR

0.84 (0.74-0.95) (95% CI)

Adjusted Vasopressor Dose Equivalence, aOR

1.03 (1.01-1.05) (95% CI)

Observational data: associations, not effects.

Further findings

SOFA ≥17 at ECMO cannulation for predicting arterial line-related limb ischemia · time of ECMO cannulation

Sensitivity
80%
Specificity
87%

Original publication

What Factors Are Associated With Arterial Line–Related Limb Ischemia in Patients on Extracorporeal Membrane Oxygenation? A Single-Center Retrospective Cohort Study. J Cardiothorac Vasc Anesth. Published 19 August 2023. doi:10.1053/j.jvca.2023.08.131

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.