What Is Sepsis, Who Gets It, How, and Why? The Keys to Unlocking Precision Medicine in Sepsis
Study context
- Population
- Patients with sepsis
Main finding
As reported in the abstract
- Sepsis is clinically, microbiologically, pathophysiologically and immunologically highly heterogeneous due to its nonspecific clinical criteria
- Despite hundreds of clinical trials, no host-targeted therapy shown to be ubiquitously efficacious
- Review of current strategies using novel biological measurements and/or computational algorithms to identify more homogeneous subgroups based on pathogen or host characteristics or both
- Review of promising recent advances to bring these discoveries to the bedside for precision medicine in sepsis
Original publication
What Is Sepsis, Who Gets It, How, and Why? The Keys to Unlocking Precision Medicine in Sepsis. Crit Care Med. Published 23 January 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →