Wide awake local anesthesia no tourniquet (WALANT) versus ultrasound-guided axillary block in carpal tunnel release: a non-inferiority randomized controlled trial
Authors' conclusion
For outpatient endoscopic CTR, the success rate of WALANT technique is non-inferior to USGAB.
Study context
- Population
- Patients undergoing outpatient endoscopic carpal tunnel release
- Participants
- 130 patients
- Comparison
- WALANT vs ultrasound-guided axillary block (USGAB) using lidocaine
- Primary endpoint
- Success rate in providing surgical anesthesia (adequate anesthesia for surgery without the need for supplementation)
Methodological detailsprospective, single-centre, double-blind, non-inferiority
- Prospective
- Single-centre
- Double-blind
- Non-inferiority
Primary result
As reported in the abstract
P < 0.05
Further findings
Postoperative ability to dress
P < 0.001
Other postoperative function
- Similar in both groups
RA satisfaction scores
- No statistical differences except discomfort elements improved with WALANT (p<0.05)
Safety
| Outcome | P value |
|---|---|
| Surgical assessment of intraoperative bleedingSimilar in both groups | P = 0.37 |
Original publication
Wide awake local anesthesia no tourniquet (WALANT) versus ultrasound-guided axillary block in carpal tunnel release: a non-inferiority randomized controlled trial. Reg Anesth Pain Med. Published 13 November 2025. doi:10.
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