Perioperative medicine & outcomes
A long duration of intraoperative hypotension is associated with postoperative delirium occurrence following thoracic and orthopedic surgery in elderly
Authors' conclusion
Intraoperative hypotension (MAP ≤65 mmHg) for ≥5 mins was associated with an increased incidence of POD after thoracic and orthopedic surgery in elderly.
Study context
- Population
- Elderly undergoing thoracic and orthopedic surgery, January 2021 to July 2022
- Participants
- 605 elderly
- Exposure
- Long or short duration of intraoperative hypotension vs no hypotension
- Outcome
- POD incidence (confusion assessment method (CAM) or CAM-ICU)
- Follow-up
- Three days after surgery
Main finding
As reported in the abstract
POD incidence · within three days after surgery
Each group vs no hypotensionAdjusted odds ratio (95% CI)P value
Long duration
3.93(2.07–7.45)
P < 0.001Short duration
1.18(0.56–2.50)
P = 0.671- Overall postoperative delirium (POD) incidence
- 14.7% (89 of 605)
Observational data: associations, not effects.
Original publication
A long duration of intraoperative hypotension is associated with postoperative delirium occurrence following thoracic and orthopedic surgery in elderly. J Clin Anesth. Published 19 April 2023. doi:10.
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