Cardiothoracic & vascular anesthesia

A New Functional Threshold for Minimally Invasive Lobectomy

Ann SurgPublished Retrospective cohort study

Authors' conclusion

The ppoFEV 1 /ppoDLCO threshold of <45% more accurately classified patients for cardiopulmonary complications after MIS lobectomy

Study context

Population
Patients undergoing minimally invasive surgery (MIS) lobectomy for clinical stage I to II lung cancer, 2018 to 2022
Participants
946 patients
Exposure
ppoFEV1/ppoDLCO threshold <45% vs current guideline threshold <60%
Outcome
Proportion correctly classified for cardiopulmonary complications after MIS lobectomy
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Proportion correctly classified

P < 0.001

Observational data: associations, not effects.

Further findings

Prolonged air leak, ppoFEV1/ppoDLCO 45% to 60% vs >60% · biggest difference in incidence among complications

P < 0.001

Predicted probability of cardiopulmonary complications by definition

Higher for Society of Thoracic Surgeons (STS) definition than European Society of Thoracic Surgeons (ESTS) or Berry definitions across ppoFEV1 and ppoDLCO values

Original publication

A New Functional Threshold for Minimally Invasive Lobectomy. Ann Surg. Published 10 May 2024. doi:10.1097/sla.0000000000006343

Composed by AI from the published abstract and checked against it. How Briefs are made →

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